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2012 Jun 1;132(3):1429-1435

CAN Management strategies for severe CAN, particularly orthostatic hypotension, focus on alleviating symptoms, extending standing time, enhancing physical capacity, and improving overall activity levels rather than solely increasing standing blood pressure
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One of its core mechanisms lies in the activation of the AMPK/PGC-1 signaling pathway

Using the homologous sequence search, we identified glutathione biosynthetic enzymes (Gcs1 and Gcs2), glutathione peroxidase (Gpx1), glutathione reductase (Glr1), and a family of glutathione S-transferases (Gsts)
