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This is because oxidative damage can result in genomic instability, DNA mutations, and tumorigenesis and progression

iFSP1 is less efficient than the genetic deletion of FSP1, whereas iFSP1 treatment in the FSP1-knockout background has no additive effect on RSL3-induced ferroptosis

Tumor Necrosis Factor Alpha Induces Stronger Cytotoxicity in ABCG2-Overexpressing Resistant Breast Cancer Cells Compared With Their Drug-Sensitive Parental Line