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Data from a systematic review of 81 epidemiological studies indicate that alcohol and smoking are independent risk factors for worse overall and HCC-specific mortality [106]
The proposed mechanisms range from well-validated (FDA-approved GLP-1 agonists for weight loss) to highly speculative (epitalon, thymosin alpha-1, MOTS-c) with limited or no human clinical validation
,,BhatSS,AhmedS,RejiR,MehtaP,PaulAMohananMet al.Efficacy and safety of curcumin in maintaining remission during disease-modifying antirheumatic drug withdrawal in rheumatoid arthritis at 52 weeks: A phase III double-blind, randomized placebo-controlled trial.2023;43(12):21932200
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