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Phase Maximum dose Weeks 17-20+ Weekly Dose 12 mg Notes Highest dose studied

Polyubiquitination of p53 by a ubiquitin ligase activity of p300

TB-500 exhibits biphasic regulation of the inflammatory response

Using hepatocellular carcinoma (HCC) as a model, we investigated the effects of exogenous antioxidants N -acetylcysteine (NAC) and glutathione (GSH) on tumor formation and growth
