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This review systematically describes the multi-target mechanisms of SIRT1 in MASLD pathogenesis through its regulation of critical factors, including peroxisome proliferator-activated receptor gamma coactivator 1-, Forkhead Box O, and nuclear factor kappa-light-chain-enhancer of activated B cells, which govern hepatocyte lipid remodeling, mitochondrial quality control, autophagyendoplasmic reticulum stress balance, and Kupffer cell/T cell polarization

A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis

It is clear that both aerobic exercise and strength training can prevent or delay cognitive decline in older adults, regardless of their current cognitive status

CD8(+)NKT-like cells regulate the immune response by killing antigen-bearing DCs
