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Research indicates that it enhances collagen synthesis and supports the remodeling of the extracellular matrix, making it valuable for treating skin wounds and burns

2020 Feb 9;9(2):474

The population frequency of the rs1801222A allele is 20%, ranging from 15% in East Asians to 29% in Europeans [31], suggesting that the variant will impact all population groups treated with metformin

To further confirm metabolic competence in selected liver cell models (PHH, HepG2 cells), CYP mRNA expression was investigated by quantitative polymerase chain reaction (qRT-PCR)