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To test this, we looked for regions of LOH where high predicted neo-antigenicity and high rates of non-synonymous mutations were mutually exclusive, finding no such inverse association in 7 of 8 patients tested (Supplementary Table 9), although several patients could not be tested due to low numbers of mutations

Furthermore, ROS can induce DNA damage in sperm, which can also contribute to structural deformities

Wang X, Wang J, Shi X, Pan C, Liu H, Dong Y, Dong R, Mang J, Xu Z