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Moreover, metformin exerts protective effects on skeletal tissue by preventing glucose- and lipotoxicity-induced osteoblast apoptosis and mitigating type 2 diabetes mellitus-associated bone deterioration

Supporting its role in fat regulation, studies in animal models have shown that FMO3-knockout mice exhibit reductions in fat mass, including visceral and subcutaneous fat [30]

Law, JR

Endoplasmic Reticulum Stress Signalling and the Pathogenesis of Non-alcoholic Fatty Liver Disease
