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Additional benefits of viral vectors include their persistence in cells as extra-chromosomal plasmids, limiting risk of insertional DNA mutations in the host [203, 208], and their ability to cross the bloodbrain barrier, allowing for intravenous delivery [205]
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E.RehaA.ElfringG.AtkinsonL.CwikV.et al (2013)
At designated time intervals, 2 ml aliquots of the release medium were withdrawn and replaced with an equal volume of the medium
