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Description
The present study demonstrated that NNMT inhibitor administered during adipocyte differentiation blocked the accumulation of lipid droplets, suggesting suppressed lipogenesis and programed development of mature adipocytes from pre-adipocyte 3T3-L1 precursor cells (i.e., adipogenesis)

Therefore, the methylation of NA catalyzed by NNMT is inhibited, and the product, MNA, is reduced
These results demonstrate that 5-amino-1MQ effects on weight loss occur through enhanced metabolic efficiency rather than appetite suppression

Another proposed mechanism involves competing interactions at growth factor receptor sites
