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In SH-SY5Y cell models, idebenone enhanced autophagy and reduced the accumulation of synuclein, suggesting a potential therapeutic strategy against Parkinsons disease [20, 21]

Further, a study focused on the angiogenic effect and counteraction of limb ischemia demonstrated that BPC 157 itself not only increased the VEGFR2 expression in vascular endothelial cells several hours after treatment but also immediately triggered the internalization of VEGFR2 within minutes [122]

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All patients with a missing MMSE score at index date were excluded from the analyses