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After age 25, you lose about 1% of your collagen each year, which is why skin starts looking less plump and more lined over time
Lipid peroxidation products (plasma F2 isoprostane) were reduced by 22.9% after Pycnogenol intake and by 3.7% in the placebo group
Note that although the brain represents only about 2% of the body weight in humans, it consumes about 20% of the total oxygen, and about 90% of this oxygen is utilized by mitochondria to produce ATP
