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Data through 2009 from the Framingham Heart Study were used to estimate lifetime risk of clinical Alzheimer's dementia by age and sex.A4 , 329 As shown in Figure 7, the study estimated that the lifetime risk for clinical Alzheimer's dementia at age 45 was approximately 1 in 5 (20%) for women and 1 in 10 (10%) for men

Funding This work was supported by National Natural Science Foundation of China (81771140), Youth Medical Talent Program of Jiangsu Province (QNRC2016068), and Medical Innovation Team of Jiangsu Province (CXTDA2017030)

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