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Sphingolipids and APOE4 in the Pathogenesis of AD Sphingolipids form a class of biologically active lipids that are important constituents of biomembranes (Loewith et al
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We show that the PPP generates NAPDH to support GSSG recycling, which facilitates oxidative protein folding, sustains ER proteostasis and prevents ferroptosis during chondrocyte differentiation
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