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Psoriasis patients were found to have increased amounts of LL-37 in their skin lesions, and it appears to promote inflammation by activating plasmacytoid dendritic cells and inducing an autoimmune response-like process

Thus, the essential significance goes to each of the substances designated to be a neurotransmitter, and thereby, the pleiotropic significance of the acknowledged neurotransmitters such as acetylcholine, histamine, dopamine, glutamine, glycine, GABA, noradrenaline, and adrenaline [12,13,14]

10.1016/j.clinbiochem.2016.10.006 18 ChenD.LiL.DiazK.IyamuI

Nat Genet 25:195200 Gazyakan E, Hennegriff M, Haaf A, Landwehrmeyer GB, Feuerstein TJ, Jackisch R (2000) Characterization of opioid receptor types modulating acetylcholine release in septal regions of the rat brain