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When using dilute acetic acid (0.1% v/v) as a solvent, it can improve initial solubilization of certain peptide batches, but the solution pH should be adjusted to near-physiological range before administration to avoid tissue irritation at the injection site in animal models

Local stabilization of hypoxia-inducible factor-1 controls intestinal inflammation via enhanced gut barrier function and immune regulation

(832) Gaucher, F

The scientific interest in this combination stems from the possibility of observing, in controlled experimental models, complementary biological pathways involved in cellular migration, stress response, actin dynamics, and structural repair processes