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About the doctors Albert Khouri, MD Associate professor of ophthalmology Rutgers New Jersey Medical school Newark, New Jersey Daniel Lee, MD Clinical instructor of ophthalmology Wills Eye Hospital Philadelphia, Pennsylvania Janet Serle, MD Professor emeritus of ophthalmology Icahn School of Medicine at Mount Sinai New York, New York References Weinreb RN, et al

2021;9:e001872

KEGG analysis identified key signaling pathways in RA-FMS comorbidity, with the serotonergic synapse pathway mainly mediating serotonin-regulated neurotransmission processes through synthesis, release, receptor subtype-specific binding, SERT transporter reuptake, dynamic regulation of mood, pain perception, and cognitive function

Furthermore, we explore the emerging concept of GS moonlighting functions, revealing its roles in palmitoylation, cell cycle regulation, and ion channel modulation