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doi: 10.1016/S1474-4422(19)30320-5 22

Regarding the definition of OP, 32.4% (n = 12) of participants wrongly identified this disease as a lack of calcium in bone and as bone inflammation disease

The use of IGF-1 as a marker becomes even more important if the GH receptor antagonist pegvisomant is used as a treatment as this form of therapy means that circulating levels of GH are no longer suitable to monitor the status of the disease [46,47]

Similarly, for oral administration of pure panduratin A, approximately 22% and 1% of the administered dose was excreted unchanged in the feces and urine, respectively, within 072 h