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Telomeres are repetitive DNA sequences that act like the protective caps at the end of chromosomes, similar to shoelace tips that keep laces from fraying

While nutritional VC intake demonstrates chemopreventive effects by scavenging carcinogen-induced reactive oxygen species (ROS) and maintaining genomic stability, high-dose intravenous VC acts as a prooxidant to selectively kill tumor cells via ROS-mediated deoxyribonucleic acid (DNA) damage, adenosine triphosphate (ATP) depletion, and HIF-1 degradation

The detailed list of copy numbers for the structural and nonstructural proteins is given in Supplementary Data 9