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Consequently, strategies aimed at modulating HIF-1 to ameliorate local hypoxic conditions may hold significant therapeutic potential for patients with AIDs ( Figure 4 )

Similarly, 24 of these bioactive granules were predicted in Lian-Ge granules composed of Coptis and Radix gerber, Salvia miltiorrhizae, seaweed, resveratrol, and taurine, which have blood-sugar-lowering properties, including berberine, puerarin, danshinolic acid A, and sinigrin, and can affect nine targets and 111 metabolic-related pathways
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