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Description
At the same time, the inhibitory effect of CB-839 makes AML cells more sensitive to adjuvants of the mitochondrial redox state, such as arsenic trioxide and hypertriglyceride [8]
Tetra thiomolybdate is considered as drug of choice in initial stages because of its rapid control of free copper, preservation of neurologic function, and low toxicity
Sample size Allowing for potential participant attrition, the total sample size for the study is 60 (30 per arm)
Importantly, astrocytes are involved in both exacerbation of damage and in neuroprotective mechanisms that are crucial for neuronal survival
