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The enzyme removes a 3C ketol group (dihydroxyacetone) from sedoheptulose 7-phosphate and transfers it to glyceraldehyde 3-phosphate, forming fructose 6-phosphate
When animals were treated with the mitochondria-targeted MnSOD mimetic Mito-TEMPO, the prevention of peroxynitrite formation due to superoxide dismutation eliminated necrotic cell death 6 h after APAP administration with no evidence of apoptosis [29, 58]
