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Fluids and solutes are transported between cells
44 The other invasive approach, temporarily opening the BBB, necessitates collaboration with highly trained neurosurgeons and it may cause potential adverse effects from BBB disruption, such as hemorrhage and brain damage or inflammation
Overall, -Arr-dependent signaling has been demonstrated most thoroughly for the mitogen activated protein kinases (MAPK) cascades: ERK, c-Jun amino-terminal kinase, p38 (Burghi et al., 2021

Experimental Neurology, 345 , Article 113812
