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Acknowledgements This work was supported by the National Key Research and Development Program of China 202lYFA1000200 and 2021YFA1000203 (YL

VE content can be calculated by measuring the OD value at 532 nm

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One of the most commonly used experimental models of IBD is the administration of an enema containing the contact-sensitizing allergen trinitrobenzenesulfonic acid (TNBS) in ethanol resulting in the development of macroscopic, histologic, and biochemical alterations that are well-characterized (Rachmilewitz et al, 1989