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Sickle Cell Disease Although only a single, small, dose escalation Phase 1 trial has been run, a limited number of disease-relevant pharmacodynamic endpoints were queried, and safety was evaluated through a relatively high calculated dose [74]
Marcus RK, Lillemoe HA, Rice DC , Mena G, Bednarski BK, Speer BB, Ramirez PT, Lasala JD, Navai N, Williams WH, Kim BJ, Voss RK, Gottumukkala VN, Aloia TA
Published research has reported: BPC-157 has been studied at 0.52 g/mL in cell culture systems and 150375 g in murine preclinical models
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