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From a pharmacological standpoint, several considerations are relevant: Gastrointestinal effects : Retatrutide, like other GLP-1-based therapies, commonly causes nausea, vomiting, diarrhoea, and reduced appetite

In children, it has most often been used at 50100 mg/kg by mouth daily

[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Schn M.P

However, for more invasive options like subcision or microneedling, you may have minimal downtime
