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One innovative strategy employed the layer-by-layer assembly technique to coat liposomes loaded with IL-12 ( Figure 3B ) ( In vitro fluorescence microscopy revealed distinct behaviors: liposomes with HA as the terminal layer were effectively internalized by two cancer cell lines, whereas PLE-coated liposomes bound to the cell surface membrane without significant uptake across multiple cell types

Stilbenes, especially resveratrol, are present in grapes, peanuts, and red wine, demonstrating antioxidant, anti-inflammatory, along with cardioprotective properties [24]

doi: 10.1038/s41577-019-0131-x 2 IwasakiAMedzhitovR

For these reasons, we used PG as the main permeating CPA to test the effect of freezing temperature (10 C vs 15 C) and storage duration (1 vs 5 days) on viability after partial freezing