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The absolute difference between these two values is 1.09 logS unit
BBB remains the preliminary physiological barrier that limits brain accessibility

Example (for a 50mg vial reconstituted in 2 mL of BAC water): Total peptide: 50mg BAC water added: 2 mL Resulting concentration: ~25 mg/mL Recommended practice: Use sterile bacteriostatic water (0.9% benzyl alcohol) for reconstitution

Crizotinib is an ATP competitive multi-target protein kinase inhibitor that targets c-Met, ALK, and ROS1 (Takiguchi et al., 2017)