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This Review describes the versatile chemical biology of RSS with focus on persulfide formation on cysteine residues

doi: 10.3389/fimmu.2025.1611932 Received 15 April 2025 Accepted 27 July 2025 Published 12 August 2025 Volume 16 - 2025 Edited by Rosalia Cuahtecontzi Delint, University of Glasgow, United Kingdom Reviewed by Arunika Mukhopadhaya, Indian Institute of Science Education and Research Mohali, India Gael Y

(21-23) Similarly, studies of humans to determine the risk of developing cirrhosis from alcohol have concluded that 50% of the phenotypic variation in terms of development of liver disease can be attributed to genetic factors

Genetic variants can influence the timing and extent of graying, while oxidative stress from ROS can damage melanocytes