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2011 Mar;24(2):262-5

116,123-125 One randomized placebo-controlled trial that included 44 subjects, aged 50 to 70 years, with memory and concentration complaints, anxiety, and sleep problems found 12 weeks of magnesium L-threonate supplementation, at a dose of 1.52 grams per day depending on body weight, significantly improved overall cognitive performance relative to both baseline and placebo

doi:10.4103/jhrs.jhrs_70_21

Clients with underlying medical issues and/or a history of poor health, diabetes, thyroid conditions, endocrine conditions, or any other health-related conditions that may contribute to weight gain or a compromised metabolism may not respond to the proposed treatment and/or may require additional treatment sessions.