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Furthermore, FOSs enhanced the skin barrier function by altering the proportion of linoleic acid (18:2) esterified omega-hydroxy-ceramides (EOS-CERs), with significantly decreased levels of amide-linked short-chain fatty acids (C28 and C30)

This approach will not only enhance our understanding of the potential role of hydrogen in the chronic progression of PD but also provide more reliable experimental evidence for clinical translational research

doi: 10.3389/fimmu.2025.1695321 Received 29 August 2025 Accepted 27 October 2025 Published 06 November 2025 Volume 16 - 2025 Edited by Francisco Jose Roig, Universidad San Jorge, Spain Reviewed by Pooja Rani Mina, Mayo Clinic Arizona, United States Shreyashi Pal, Birla Institute of Technology, India Updates Copyright 2025 Li, Yuan, Huang and Wang