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Elevated portal vein glucose levels trigger lateral hypothalamic activation, stimulating the parasympathetic nervous system and promoting hepatic glycogen synthesis
the Km value of LCMT-1 for PP2AD was 0.1 M [170]

[137] While it's possible that intravenous vitamin C might not be effective after ischemic stroke when oxidative damage has already occurred, another possible explanation for the lack of efficacy observed in this study was the low dose used, since intravenous vitamin C doses are typically administered in gram quantities