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Studies had identified that organic cation transporter 2 (OCT2, SLC22A2) mediates TMAO uptake into renal proximal tubular cells and that multiple transporter of the ATP-binding cassette (ABC) family, including ABCG2 (BCRP) and ABCB1 (MDR1), are capable of TMAO efflux (Miyake et al., 2017

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Cao SS, Zimmermann EM, Chuang BM, Song B, Nwokoye A, Wilkinson JE, et al
