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Therefore, the potential adverse influence of senolytics needs to be further investigated
FIGURE 1 Cocaine The World Drug Report estimates that worldwide, 18.8 million people used cocaine in 2014 (United Nations Office on Drugs and Crime, 2016)
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Chronic dosing studies including protocols running daily administration for 4 to 12 consecutive weeks have not documented significant organ toxicity markers at doses ranging from 10 to 100 g/kg
