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The shared molecular binding of the brains vitamin B 12 carrier protein, known as transcobalamin 2 or TCN2, with the FDA-approved MS drug fingolimod provides a mechanistic link between B 12 signaling and MS, towards reducing neuroinflammation and possibly neurodegeneration, said Chun
"The role of homocysteine-lowering B-vitamins in the primary prevention of cardiovascular disease"
The added GIP activity appears to synergistically amplify metabolic effects beyond GLP1 alone, contributing to superior weight reduction observed in clinical trials [3] [4]
