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[DOI] [PMC free article] [PubMed] [Google Scholar] 101.Jamieson PM, Cleasby ME, Kuperman Y, et al

Early research suggests good safety when administered under medical supervision

Many people with a deficiency describe deep fatigue, including an "afternoon crash." With infrequent dosing, blood levels can peak and then taper before the next visit

Individuals with repeated injuries show increased risk for greater cognitive impairment and persistence of symptoms
