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Description
It employs a deductive analysis of the failures to determine which combination of lower-level, or primary failures can combine to cause a critical event or an undesired state of the fielded system

This phenotypic plasticity underscores macrophages as the central orchestrators of immune-mediated renal injury in DKD ( Figure 2 )

10.1016/j.neuint.2010.02.004 Neurochem
Further research is needed to fully understand DSIPs molecular mechanisms and potential therapeutic agent applications
