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[DOI] [PubMed] [Google Scholar] 198.Huang T., Zhang K., Sun L., Xue X., Zhang C., Shu Z., Mu N., Gu J., Zhang W., Wang Y., et al

Although the majority of the studies are on rodents, there are a few promising human trials

In a similar vein, much of the available research based on animal models overlooks the inherent limitations of these systems and the potential for misleading results

This specific targeting of the inflammasome is a sophisticated mechanism that is not universally reported for all anti-inflammatory polysaccharides and represents a key advantage as dysregulated NLRP3 activity is implicated in a wide range of chronic inflammatory and metabolic diseases