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Several other investigators have also revealed that the activation of IGF-1R stimulated the p53-dependent cellular senescence, e.g., in human and mouse fibroblasts, human mesangial cells, and rat vascular smooth muscle cells [144,145,146]

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It leads to increased oxidative stress, alterations in mitochondrial bioenergetics, or impaired mitochondrial transport to synapses [1,2,166]

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Epinephrine secretion is mediated through nicotinic receptors on adrenal chromaffin cells (27)

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Affinity chromatography uses thiol-reactive resins (e.g., pyridyl disulfide agarose) to enrich disulfide-containing species

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