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Description
Upon binding to its specific receptors, EP2 and EP4, PGE2 activates various signaling cascades, including STAT3, CREB1, and NF-B, to upregulate IL-23R expression on Th17 cells

In high-risk CRC populations, acetate concentrations are significantly lower, suggesting that acetate may have a potential protective role in the prevention of CRC

Curr Pharmacol Rep
Bedse G, Di Domenico F, Serviddio G, Cassano T
