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Before treatment with OPZELURa Before treatment with OPZELURa AT ~2 months of treatment with OPZELURA AT ~2 months of treatment with OPZELURA AT ~8 months of treatment with OPZELURA AT ~8 months of treatment with OPZELURA AT ~12 months of treatment with OPZELURA at ~12 months of treatment with OPZELURA AT ~2 years of treatment with OPZELURA AT ~2 years of treatment with OPZELURA Sam used OPZELURA alone for treatment of vitiligo on her face and neck

10.1101/gr.267013.120 32 ChenF.JimenezR

& Kiyama, H

So, DR could play an especially important role in enhancing the function of aged hippocampal oligodendrocytes to support neuronal and cognitive function by increasing GPD1 levels to increase G3PS activity as well as by increasing glycerol-3-phosphate levels for the synthesis of phospholipids, which contribute to the synthesis of myelin