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(PubMed) Chen Y, Abbate M, Tang L, et al

Apos-mediated the activation of ECs may generate multiple cytokines, such as interleukin (IL)-6, IL-8, intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and so on, which incite the recruitment of monocytes and adhesion to ECs 17-19

Due to its unique receptor profile, Melanotan II has become a reference compound in pigmentation research, photobiology, and melanocortin system studies

The fluence (energy per unit area) must be sufficient to raise follicular temperatures to lethal levels while remaining below the threshold for epidermal damage