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This study reveals that by targeting the UBE2C-ubiquitination axis, SAHA coordinates the regulation of protein degradation and the epithelial-mesenchymal transition (EMT) process (117)
DNA damage activates PARPs that can use up to 90% of the cell's NAD+, which makes DNA repair heavily reliant on NAD+ availability
Li Q, Ren J: Influence of cardiac-specific overexpression of insulin-like growth factor 1 on lifespan and aging-associated changes in cardiac intracellular Ca2+ homeostasis, protein damage and apoptotic protein expression
npj Antimicrob Resist 3 , 24 (2025)
