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extract following intraperitoneal administration with a lethal dose of APAP was found to be protective against APAP-induced necrosis by downregulating the cytochrome P450 CYP2E1 protein levels in vitro (Hau et al., 2009)
Biochem J 49:593601 Marty L, Bausewein D, Mller C, Bangash SAK, Moseler A, Schwarzlnder M, Mller-Schssele SJ, Zechmann B, Riondet C, Balk J, Wirtz M, Hell R, Reichheld JP, Meyer AJ (2019) Arabidopsis glutathione reductase 2 is indispensable in plastids, while mitochondrial glutathione is safeguarded by additional reduction and transport systems

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doi: 10.1038/s41541-021-00294-8 300 OliverJ