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PLoS ONE 8 , e71982 (2013)

CJC-1295 with DAC produces a sustained, flat elevation of basal GH output that is more HGH-like than GHRH-like, which is why it is often combined with a short acting GHS to reintroduce pulses

In this study, changes to serum GSSG levels were positively correlated with reductions in both PANSS total scores and positive symptom scores among ECT responders, indicating that changes to the redox state occurred in parallel with clinical symptom improvement

This indicates that both pathways are irreversible in vivo