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While dyskinesia is correlated with L-DOPA usage, the disease itself (PD) and a pulsatile drug delivery are both required for dyskinesia to develop
Glutathione, one of the most potent free radical scavengers, is recycled via the flavin dependent activity of the enzyme glutathione reductase [75], and reduced flavins levels correlate with glutathione depletion [76]
The kidney is the main site of the disposition of APAP sulfate, either through direct excretion or through further biotransformation followed by renal excretion
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