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Description
At one end of the spectrum, metabolic dysfunction-associated steatotic liver (hepatic steatosis, MASL) may progress to a more advanced state called metabolic dysfunction-associated steatohepatitis (MASH) characterized by significant hepatocyte damage, inflammation, and pericellular fibrosis, and further to cirrhosis (Friedman et al
doi: 10.3390/ijms140610979 128 MarkusRPFernandesPAKinkerGSda Silveira Cruz-MaChadoSMarcolaM
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NAD + deficiency can impair the PPP's ability to produce NADPH via decreased hexokinase activity [490,491,492]
