dsip vs melatonin for Deep Sleep: Benefits, Dosage & Safety DSIP works but most times
Description
Research indicates that interactions within the HGF system may initiate downstream signaling pathways, including kinase-mediated cellular responses and intracellular messenger activation
Importantly, nuclear-localized FOXO4-positive Leydig cells in elderly testes showed reduced expression of 3-HSD, a rate-limiting enzyme in testosterone synthesis, implying a connection between nuclear FOXO4 and age-related decline in testosterone production [1]

PubMed Central, Lahner, Edith, et al

These effects are usually mild and resolve quickly
