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observed in human keratinocytes that IR-induced GSH depletion occurred despite unchanged expression of SLC7A11 and apparent upregulation of Glutamate-Cysteine Ligase, the rate-limiting enzyme responsible for GSH synthesis, suggesting the role of another GSH regulator [38]
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The antioxidant EPC-K1 attenuates renal ischemia-reperfusion injury in a rat model
Animal studies and small human trials support AOD-9604's lipolytic effect
