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Consistent with the results from germline XKR8 KO mice challenged with LPS, neutrophil-specific XKR8 KO mice displayed significantly reduced NET formation in the lungs, lower levels of extracellular dsDNA in BALF and mitigated lung injury, despite similar levels of neutrophil infiltration following LPS challenge (Fig
Furthermore, unlike GSH, NAC can cross the phospholipid bilayer of the plasma membrane of cells
Uto-KondoHAyaoriMKishimotoYAdachiTTakiguchiSYakushijiEet al
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